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Adverse reactions associated with skin testing and immunotherapy
1Division of Allergy and Immunology, University of South Florida College of Medicine, Tampa 33612, USA.
Summary
Allergen immunotherapy and skin testing carry risks, including fatal anaphylaxis. Physicians must be trained to manage these risks and treat anaphylaxis to ensure patient safety during allergy treatments.
Area of Science:
- Allergy and Immunology
- Clinical Medicine
Background:
- Allergen skin testing and immunotherapy are established allergy treatments.
- These procedures carry a risk of severe adverse events, including anaphylaxis.
Purpose of the Study:
- To highlight the risks associated with allergen immunotherapy and skin testing.
- To emphasize the importance of physician preparedness in managing anaphylaxis.
Main Methods:
- Review of adverse events associated with allergen immunotherapy and skin testing.
- Discussion of current recommendations for patient monitoring and physician training.
Main Results:
- Fatalities have been reported in association with allergen skin testing and immunotherapy.
- The American Academy of Allergy and Immunology recommends specific waiting periods post-injection and physician preparedness for anaphylaxis treatment.
Conclusions:
- Physicians must be knowledgeable in the use of allergen skin testing and immunotherapy.
- Proper precautions and preparedness for anaphylaxis are crucial to minimize risks and ensure patient safety.