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Autonomic disorders in Parkinson's disease
E Martignoni1, C Pacchetti, L Godi
1Department of Neurology, Parkinson's Disease Centre, IRCCS-C.Mondino, University of Pavia, Italy.
Journal of Neural Transmission. Supplementum
|January 1, 1995
Summary
Idiopathic Parkinson's disease (IPD) frequently causes autonomic dysfunction, including constipation (73%), urinary issues (37-71%), and orthostatic hypotension (15%). These symptoms impact quality of life and disease progression.
Area of Science:
- Neurology
- Autonomic Neuroscience
Background:
- Idiopathic Parkinson's disease (IPD) is frequently associated with autonomic nervous system dysfunction.
- These autonomic symptoms can significantly impact patient quality of life and disease management.
Purpose of the Study:
- To review the common autonomic dysfunctions observed in patients with idiopathic Parkinson's disease.
- To highlight the prevalence and types of autonomic symptoms in IPD patients.
Main Methods:
- Literature review of studies reporting autonomic symptoms in idiopathic Parkinson's disease.
- Analysis of reported symptom frequencies and clinical associations.
Main Results:
- Constipation is highly prevalent, affecting approximately 73% of IPD patients, linked to motor control deficits.
- Urinary symptoms, including urgency and incontinence due to detrusor hyperreflexia, occur in 37-71% of cases.
- Cardiopressor adaptability failure leading to orthostatic hypotension affects around 15% of patients, often in later disease stages or related conditions.
Conclusions:
- Autonomic dysfunction is a common and significant feature of idiopathic Parkinson's disease.
- Recognizing and managing these symptoms is crucial for comprehensive patient care in IPD.