Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Risperidone: efficacy and safety

D Umbricht1, J M Kane

  • 1Hillside Hospital, Division of Long Island Jewish Medical Center, Glen Oaks, NY 11004, USA.

Schizophrenia Bulletin
|January 1, 1995
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Canadian Surgery Forum: Abstracts of presentations to the Annual Meetings of the Canadian Association of Bariatric Physicians and Surgeons, Canadian Association of General Surgeons, Canadian Association of Thoracic Surgeons, Canadian Hepato-Pancreato-Biliary Society, Canadian Society of Surgical Oncology, Canadian Society of Colon and Rectal Surgeons, London, Ont. Sept. 15-18, 2011.

Canadian journal of surgery. Journal canadien de chirurgie·2022
Same author

A white paper on a neurodevelopmental framework for drug discovery in autism and other neurodevelopmental disorders.

European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology·2021
Same author

Letter to the editor referring to P.S Aisen and R. Raman, Futility Analyses in Alzheimer's Disease (AD) Clinical Trials: A Risky Business. The Journal of Prevention of Alzheimer's Disease, 2020.

The journal of prevention of Alzheimer's disease·2020
Same author

How and when to use clozapine.

Acta psychiatrica Scandinavica·2019
Same author

Detecting relapse in youth with psychotic disorders utilizing patient-generated and patient-contributed digital data from Facebook.

NPJ schizophrenia·2019
Same author

Clozapine as an early-stage treatment.

Acta psychiatrica Scandinavica·2018
Same journal

The Effect of Semaglutide on Antipsychotic-Induced Weight Gain and Other Metabolic Parameters, among a Cohort of Inpatients.

Schizophrenia bulletin·2026
Same journal

Comparing Apples to Oranges Obscures Tortoises Beating Hares: The Relationship Between Rate of Antipsychotic Tapering and Relapse.

Schizophrenia bulletin·2026
Same journal

Beyond the Need for Speed: D2 Receptor Affinity Predicts Relapse after Antipsychotic Tapering in First Episode Psychosis.

Schizophrenia bulletin·2026
Same journal

Correction to: The Mini-CAARMS: Development and Validation of a Short Version of the Comprehensive Assessment of AT Risk Mental States to Facilitate Preventive Psychiatry.

Schizophrenia bulletin·2026
Same journal

Longitudinal Impact of Birthweight and its Polygenic Risk Score on Glucose and Antipsychotic-Induced Weight Gain in First Episode Psychosis.

Schizophrenia bulletin·2026
Same journal

The Key to Clozapine Mystery May Lie in its Shape.

Schizophrenia bulletin·2026
See all related articles

Risperidone demonstrates superior antipsychotic efficacy compared to placebo in acute schizophrenia. Its effectiveness is comparable to other antipsychotics, but further research is needed for long-term use.

Area of Science:

  • Psychiatry
  • Pharmacology
  • Clinical Medicine

Background:

  • Schizophrenia is a chronic mental disorder.
  • Antipsychotic medications are the cornerstone of treatment.
  • Risperidone is an atypical antipsychotic used for schizophrenia.

Purpose of the Study:

  • To review the evidence for risperidone's efficacy and effectiveness in schizophrenia.
  • To compare risperidone with other antipsychotics and placebo.

Main Methods:

  • Systematic review of nine double-blind studies.
  • Studies focused on the acute phase of schizophrenia.
  • Comparisons included other antipsychotic medications and placebo.

Main Results:

Related Experiment Videos

  • Risperidone showed consistently superior antipsychotic efficacy over placebo.
  • Efficacy was comparable to haloperidol and perphenazine in acute schizophrenia.
  • Effectiveness in maintenance treatment and specific patient groups requires further investigation.

    • Conclusions:

    • Risperidone is effective in treating acute schizophrenia.
    • Further research is needed to establish long-term effectiveness and efficacy in refractory or deficit states.