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[Mononeuritis multiplex associated with measles virus infection]
Rinsho Shinkeigaku = Clinical Neurology
|February 1, 1996
Summary
A 19-year-old experienced mononeuritis multiplex following measles virus infection. This rare neurological complication involved peripheral nerve damage, suggesting a potential link to persistent measles infection and vasculitis.
Area of Science:
- Neurology
- Infectious Diseases
- Virology
Background:
- Measles virus infection can present with diverse neurological complications.
- Mononeuritis multiplex is a rare but serious peripheral neuropathy.
Observation:
- A 19-year-old male developed symptoms of mononeuritis multiplex 13 days after measles recovery.
- Neurological examination revealed distal weakness and sensory disturbances in the radial and median nerves.
- Electrodiagnostic studies confirmed axonal neuropathy in affected nerves.
Findings:
- Elevated serum IgG and IgM antibody titers against measles virus persisted for over four months post-infection.
- Cerebrospinal fluid analysis and EEG were normal.
- Corticosteroid therapy showed mild effectiveness.
Implications:
- This case suggests a possible association between persistent measles virus infection and the development of mononeuritis multiplex.
- The underlying pathogenesis may involve measles-induced vasculitis affecting peripheral nerves.
- Further research is needed to elucidate the mechanisms linking measles virus to this neurological condition.