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[Coronary endoprosthesis (stents) implanted without coumadin administration: one year's experience]
A Pérez de Prado1, E J García, M Abeytua
1Departamento de Cardiología, Hospital General Universitario Gregorio Marañón, Madrid.
Revista Espanola De Cardiologia
|June 1, 1996
Summary
Coronary stenting without oral anticoagulation showed low rates of subacute occlusion and complications. This approach may be a safe alternative for patients undergoing stenting procedures.
Area of Science:
- Cardiovascular Medicine
- Interventional Cardiology
- Biomedical Engineering
Background:
- Subacute occlusion and bleeding are significant limitations in coronary stenting.
- The necessity of oral anticoagulation to prevent stent occlusion is debated.
Purpose of the Study:
- To evaluate the safety and efficacy of coronary stenting without oral anticoagulation.
- To assess the rates of subacute occlusion and bleeding complications in patients treated with a specific antiplatelet regimen.
Main Methods:
- 121 patients underwent 125 coronary stent procedures with initial angiographic success.
- Patients received intravenous heparin and aspirin during the procedure, followed by oral aspirin and ticlopidine.
- A subset of patients also received enoxaparin for 10 days.
Main Results:
- 172 stents were implanted in 148 lesions, with high-pressure deployment.
- No subacute occlusions were observed during follow-up (30-441 days).
- Bleeding and vascular complication rates were low (0.8% and 1.6%, respectively).
Conclusions:
- Coronary stenting with high-pressure dilatation and without subsequent anticoagulation is associated with low subacute occlusion rates.
- This strategy appears safe, with minimal bleeding or vascular complications.