[The establishment of osteogenesis imperfecta for personal identification]

Anatomical, clinical (including X-ray), microscopic, and ultrastructural features of osseous tissue were studied in 32 subjects suffering from congenital osteopsathyrosis, osteogenesis imperfecta, aged 0 to 38 years. The findings showed that bone tissue was sharply rarefied, with the amount of the base substance reduced and the number of osteocytes per unit of its area increased. This sign, typical of the disease in question, is still observed in putrefied corpses. Electron microscopy revealed decrease of granular endoplasmatic reticulum in osteoblasts with impaired maturation of collagen fibrils and their mineralization.