[Methods for determining the activity of factors VII, VIII, IX and X of the blood coagulation system]

The existing methods for determination of activity of the VII, VIII, IX and X factors of the coagulation system have been analyzed. The comparative evaluation of their efficiency which depends on complexity, reprocibility, sensibility and test performance time is considered. The important role of these methods in scientific investigation for the diagnosis of haemophilia A, haemophilia D, factors VII and X deficiency for the purposes of therapy is emphasized.