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Related Experiment Videos

Cordocentesis: a useful method for prenatal diagnosis

Y Xiang1, N Sun, X Chang

  • 1Peking Union Medical College Hospital, PUMC & CAMS, Beijing.

Chinese Medical Journal
|April 1, 1996
PubMed
Summary

Cordocentesis is a safe and effective prenatal diagnostic method for fetal diseases. Intrahepatic vein sampling offers an alternative when cordocentesis is unsuccessful, ensuring timely diagnosis.

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Area of Science:

  • Medical Science
  • Obstetrics and Gynecology
  • Fetal Medicine

Background:

  • Prenatal diagnosis of fetal diseases is crucial for timely intervention.
  • Cordocentesis, a fetal blood sampling technique, is utilized for various genetic and infectious disease diagnoses.

Purpose of the Study:

  • To assess the safety and efficacy of cordocentesis for prenatal diagnosis.
  • To identify alternative methods in cases of cordocentesis failure.

Main Methods:

  • Fetal blood sampling via cordocentesis in 30 pregnancies (19-36 weeks gestation).
  • Utilized ultrasound guidance and a 22-gauge spinal needle.
  • Alternative methods included intrahepatic vein sampling and cardiocentesis.

Main Results:

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  • High success rate: 25/30 first-attempt cordocentesis.
  • Procedure duration under 15 minutes in 25 cases.
  • No maternal blood contamination or lethal complications observed.

Conclusions:

  • Cordocentesis is a safe and valuable tool for prenatal diagnosis.
  • Intrahepatic vein sampling is a viable alternative when cordocentesis fails.