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[Severe contact dermatitis caused by mephenesin]
C Bachmeyer1, L Blum, M L Fléchet
1Service de Médecine Interne, Hôpital Hôtel-Dieu, Paris.
Introduction:
Mephenesin is a muscle relaxant, mostly applied locally in trauma. It is a component of Traumalgyl cream in association with phenylbutazone. Contact dermatitis due to mephenesin is exceptional.
Case Report:
We report here a case of a woman who developed after application of Traumalgyl cream purpuric dermatitis, erythema multiforme-like and urticarial lesions. Patch-tests were strongly positive (+ + +) for both Traumalgyl cream and mephenesin and (+) for phenylbutazone. Improvement of the lesions was observed within 3 weeks.
Discussion:
Physicians must be aware of the risk of severe contact dermatitis after application of products including mephenesin because of their widely prescription.