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[Peripheral neuropathies caused by disulfiram]
1Service de Neurologie, Hôpital d'Instruction des Armées Laveran, Marseille.
Revue Neurologique
|April 1, 1996
Abstract:
Disulfirame is a rare cause of peripheral neuropathy in subjects with chronic alcoholism. We report here a case in a 42-year-old man and present the main clinical features and electrophysiological and pathology results. Disulfamine-induced peripheral neuropathy is dose-dependent and never occurs below 250 mg/d (1/2 tables of Espéral*). The pathogenesis is poorly understood.