Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Multiple sclerosis and neurofibromatosis 1]

S Alfonso1, J Roquer, A Pou

  • 1Servicio de Neurología, Hospital del Mar, Barcelona.

Neurologia (Barcelona, Spain)
|June 1, 1996
PubMed
Summary

This case study details a patient with multiple sclerosis and neurofibromatosis type I, highlighting diagnostic challenges. Genetic links between these conditions are explored, impacting our understanding of neurological disorders.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Clinical profile and non-recreational methamphetamine abuse (shabu) among stroke patients in the Philippine population].

Revista de neurologia·2023
Same author

Lipidomic signature of stroke recurrence after transient ischemic attack.

Scientific reports·2023
Same author

The CORCOBIA study: Cut-off points of Alzheimer's disease CSF biomarkers in a clinical cohort.

Neurologia·2022
Same author

Migraine-Associated Common Genetic Variants Confer Greater Risk of Posterior vs. Anterior Circulation Ischemic Stroke☆.

Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association·2022
Same author

[Cross-cultural adaptation to Spanish of the Signs of Depression Scale (SODS) to the early assessment of mood in patients admitted to a Stroke Unit].

Revista de neurologia·2022
Same author

Air pollution and surrounding greenness in relation to ischemic stroke: A population-based cohort study.

Environment international·2022

Area of Science:

  • Neuroscience
  • Genetics
  • Radiology

Background:

  • Multiple Sclerosis (MS) is a chronic autoimmune disease affecting the central nervous system.
  • Neurofibromatosis type I (NF1) is a genetic disorder causing tumors to grow on nerves.

Observation:

  • A patient presented with recurrent-remittent multiple sclerosis concurrently with neurofibromatosis type I.
  • Magnetic Resonance Imaging (MRI) findings were challenging to interpret due to overlapping anomalies between MS and NF1.

Findings:

  • The co-occurrence of MS and NF1 presents diagnostic complexities in neuroimaging.
  • Recent genetic research indicates a potential link: the myelin protein gene ( குளோ ) is located within an intron of the neurofibromatosis-1 (NF1) gene on chromosome 17.

Implications:

  • Understanding the genetic interplay between MS and NF1 may refine diagnostic criteria for both conditions.
  • This case underscores the importance of considering genetic associations when evaluating complex neurological presentations.

Related Experiment Videos