Lipid profile norms in Indian children

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Published on: November 24, 2020

A Khalil1, S Gupta, A Madan

  • 1Department of Pediatrics, Maulana Azad Medical College, New Delhi.

Indian Pediatrics
|November 1, 1995
PubMed

Insights

This study established normal lipid profile values for Indian children aged 3-12 years. Recommended cut-off levels for total cholesterol, triglycerides, HDL-C, and LDL-C were determined, noting lower HDL-C compared to Western data.

Area of Science:

  • Pediatric lipidology
  • Public health nutrition

Background:

  • Establishing normative data for lipid parameters in pediatric populations is crucial for identifying dyslipidemia.
  • Existing lipid profile data in India may not accurately reflect current pediatric health trends.

Purpose of the Study:

  • To determine reference ranges for lipid profiles in healthy Indian children.
  • To establish cut-off values for identifying abnormal lipid levels in this demographic.
  • To compare findings with existing Western data.

Main Methods:

  • A cross-sectional, hospital-based study involving 410 Indian children aged 3-12 years.
  • Measurement of plasma total cholesterol (TC), triglycerides (TG), and high-density lipoprotein cholesterol (HDL-C).
  • Calculation of low-density lipoprotein cholesterol (LDL-C) using the Friedrickson-Friedwald formula.

Main Results:

  • No significant sex-based differences were observed in lipid parameters.
  • Mean lipid values: TC 134.5 mg/dL, TG 91.1 mg/dL, HDL-C 34.15 mg/dL, LDL-C 80.1 mg/dL.
  • Recommended cut-off limits: TC 190 mg/dL, TG 150 mg/dL, HDL-C 20 mg/dL, LDL-C 130 mg/dL.

Conclusions:

  • Normative lipid profile values and cut-off levels for Indian children were recommended.
  • Observed high-density lipoprotein cholesterol (HDL-C) levels were lower than those reported in Western populations.
  • These findings provide essential benchmarks for pediatric cardiovascular risk assessment in India.
Abstract

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