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Related Experiment Videos

Local steroid therapy in cutaneous hemangiomas

A N Gangopadhyay1, S P Sharma, S C Gopal

  • 1Division of Pediatric Surgery and Plastic Surgery, Banaras Hindu University, Varanasi.

Indian Pediatrics
|January 1, 1996
PubMed
Summary

Intralesional triamcinolone injections effectively treat rapidly growing hemangiomas, showing an 88.6% response rate. This treatment is safe and particularly beneficial for infants and facial lesions.

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Area of Science:

  • Dermatology
  • Pediatric Medicine
  • Pharmacology

Background:

  • Hemangiomas are common vascular tumors in infants.
  • Rapidly growing hemangiomas require effective treatment to prevent complications.
  • Intralesional corticosteroid therapy is a potential treatment option.

Purpose of the Study:

  • To assess the efficacy of intralesional triamcinolone for hemangioma regression.
  • To determine the response rate and identify factors influencing treatment outcomes.

Main Methods:

  • A study involving 105 pediatric outpatients with rapidly growing surface hemangiomas.
  • Intralesional triamcinolone was administered monthly (mean 3.6 injections).
  • Hemangioma regression was the primary outcome measure.

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Main Results:

  • An overall response rate of 88.6% was achieved (51.4% excellent, 37.2% good).
  • Highest efficacy was noted in infants under one year (over 90%), facial lesions (92.8%), and strawberry hemangiomas (99.9%).

Conclusions:

  • Intralesional triamcinolone is an effective treatment for rapidly growing hemangiomas.
  • The treatment demonstrated no systemic side effects.
  • It is a suitable initial therapeutic approach for pediatric hemangiomas.