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Serum prolactin in chronic hydrocephalus
1Dr. R.M.L. Hospital, New Delhi.
The Journal of the Association of Physicians of India
|September 1, 1995
Summary
Serum prolactin levels may indicate shunt efficacy in chronic hydrocephalus patients. Changes in prolactin correlate with ventricular size after cerebrospinal fluid diversion, suggesting its use as a monitoring parameter.
Area of Science:
- Neurosurgery
- Endocrinology
- Radiology
Background:
- Chronic hydrocephalus presents challenges in monitoring treatment effectiveness.
- Cerebrospinal fluid (CSF) diversion via shunts is a common treatment.
- Non-invasive markers for shunt efficacy are needed.
Purpose of the Study:
- To correlate serum prolactin levels with ventricular size in chronic hydrocephalus.
- To assess serum prolactin as a reliable parameter for shunt efficacy.
- To determine if prolactin levels change with ventricular size alterations post-CSF diversion.
Main Methods:
- Prospective study design.
- Measurement of serum prolactin levels.
- Computed tomography (CT) scans to assess ventricular size.
- Evaluation before and after CSF diversion.
Main Results:
- Serum prolactin levels showed correlation with ventricular size.
- Prolactin levels altered following effective CSF diversion.
- Findings suggest prolactin's potential as a shunt efficacy indicator.
Conclusions:
- Serum prolactin may serve as a reliable, non-invasive marker for monitoring shunt function in hydrocephalus.
- Changes in prolactin levels reflect successful CSF diversion and ventricular size reduction.