[Consensual inflammatory reaction in chemical eye burn of the rabbit eye]
S Giessler1, H G Struck, C Giessler
1Klinik und Poliklinik für Augenheilkunde, Martin-Luther-Universität Halle-Wittenberg.
Background:
Consensual ocular response has been known to occur following intracranial stimulation of the trigeminal nerve, intracameral injection of prostaglandins and other substances, after paracentesis and contusio bulbi.
Material And Method:
We have examined the prostacyclin formation in both eyes after experimental alcali burn (0.25 mo/l NaOH) on 30 rabbits with ELISA over a follow up period of 14 days.
Results:
After the alcali burn the aqueous prostacyclin level on the right eye is increased from 327 pg/ml aqueous to 27098 pg/ml aqueous, but on the left it stays normally. In conjunctiva and anterior uvea we measured normal amounts of prostacyclin.
Conclusions:
We could not find a consensual increase in prostacyclin formation in the anterior part of the fellow eye following alcali burn.
More Related Videos
08:04A Rabbit Model of Aqueous-Deficient Dry Eye Disease Induced by Concanavalin A Injection into the Lacrimal Glands: Application to Drug Efficacy Studies
Published on: January 24, 2020
07:10Ex Vivo and In Vivo Animal Models for Mechanical and Chemical Injuries of Corneal Epithelium
Published on: April 6, 2022
