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Iron and vitamins

L Hallberg1

  • 1Department of Internal Medicine, University of Göteborg, Sweden.

Bibliotheca Nutritio Et Dieta
|January 1, 1995
PubMed
Summary
This summary is machine-generated.

Ascorbic acid significantly enhances dietary nonheme iron absorption. Recommended intake is at least 50 mg per meal, adjusted for phytate content and energy expenditure.

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Area of Science:

  • Nutrition Science
  • Human Physiology
  • Dietary Supplementation

Background:

  • Ascorbic acid (vitamin C) is crucial for nonheme iron absorption.
  • Understanding the dose-response relationship and regulatory mechanisms of iron absorption is vital for nutritional health.

Purpose of the Study:

  • To elucidate the role of ascorbic acid in nonheme iron absorption.
  • To determine the dose-effect relationship and factors influencing iron absorption.

Main Methods:

  • Literature review on ascorbic acid and iron metabolism.
  • Analysis of dose-response data for ascorbic acid and iron absorption.
  • Examination of iron absorption regulatory systems.

Main Results:

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  • Ascorbic acid demonstrates a log/log dose-effect relationship with iron absorption.
  • Both natural and synthetic ascorbic acid yield similar effects.
  • Iron absorption is not impaired by prolonged high ascorbic acid intake.
  • Efficient physiological regulation prevents iron overload in healthy individuals.

    • Conclusions:

    • Adequate ascorbic acid intake is essential for optimal dietary nonheme iron absorption.
    • A minimum of 50 mg ascorbic acid per meal is recommended.
    • Increased ascorbic acid intake may be beneficial with high phytate meals or low energy expenditure.