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A new cytotoxic compound from a water extract of corn
Y Hayashi1, N Ishihara, M Takahashi
1Research Laboratories II, Tamanoi Vinegar Co. Ltd., Osaka, Japan.
Bioscience, Biotechnology, and Biochemistry
|July 1, 1996
Abstract:
A new cytotoxic compound 2 was isolated from a water extract of corn germ. Structural elucidation by spectroscopic data and chemical evidence fully substantiated 2 to be 11 (E)-10-oxo-11-octadecen-13-olide. Compound 2 exhibited considerably strong cytotoxic activity against various cell lines with IC50 of 0.9-2.8 micrograms/ml.