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Updated: Aug 14, 2026

Assessing Whole-Body Lipid-Handling Capacity in Mice
Published on: November 24, 2020
Cardiac findings in generalized lipodystrophy
P G Bjørnstad1, A Foerster, H Ihlen
1Medical Department B, Rikshospitalet, National Hospital, Oslo, Norway.
Generalized lipodystrophy (Berardinelli-Seip disease) significantly impacts cardiac health, causing hypertrophic hearts and dysfunction. This condition leads to premature death, highlighting the critical need for cardiac management in affected individuals.
Area of Science:
- Cardiology
- Genetics
- Metabolic Disorders
Background:
- Total lipodystrophy, including Berardinelli-Seip disease, is a rare genetic disorder characterized by a near-complete absence of adipose tissue.
- Cardiac complications are increasingly recognized as a major cause of morbidity and mortality in patients with lipodystrophy.
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