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Intracardiac thrombi: frequency, location, etiology, and complications: a morphologic review--Part III
B F Waller1, T McLaughlin, L Grider
1Cardiovascular Pathology Registry, St. Vincent Hospital, Indianapolis, Indiana, USA.
Insights
Intracardiac thrombus can form due to heart conditions. This part of the series examines thrombus frequency and consequences in left ventricular aneurysms after heart attacks.
Area of Science:
- Cardiology
- Cardiovascular Medicine
- Thrombosis Research
Background:
- Intracardiac thrombus is a complication of various cardiac conditions.
- Left ventricular (LV) aneurysms, often resulting from acute myocardial infarction, are frequently associated with intra-aneurysmal thrombus.
- This article is the third in a series discussing intracardiac thrombus.
Purpose of the Study:
- To investigate the frequency of thrombus formation within left ventricular aneurysms.
- To analyze the clinical consequences of intra-aneurysmal thrombus in LV aneurysms.
- To provide a focused review on LV aneurysm-associated intracardiac thrombus.
Main Methods:
- Review of existing literature on intracardiac thrombus and LV aneurysms.
- Analysis of epidemiological data regarding thrombus prevalence in LV aneurysms.
- Synthesis of clinical outcomes and embolic events associated with LV aneurysm thrombus.
Main Results:
- Left ventricular aneurysms are a significant site for intracardiac thrombus development.
- The presence of thrombus in LV aneurysms is linked to embolic events.
- Frequency and specific consequences are detailed in this review.
Conclusions:
- Intra-aneurysmal thrombus in LV aneurysms is a clinically relevant complication.
- Understanding the frequency and consequences is crucial for patient management.
- Further research may elucidate specific risk factors and preventative strategies.
Abstract:
Intracardiac thrombus may develop as a consequence of multiple underlying cardiac disorders. Left ventricular (LV) aneurysm following acute myocardial infarction has been associated with intra-aneurysmal thrombus and emboli. Part III of this 5-part article on intracardiac thrombus focuses on the frequency and consequence of thrombus associated with LV aneurysm.