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[Tumor suppressor genes]
Molekuliarnaia Genetika, Mikrobiologiia I Virusologiia
|January 1, 1996
Abstract:
The review presents data on the history of the discovery of tumor suppressor genes (antioncogenes) and the new data on their mapping and cloning. Special attention is given to the mechanisms of retinoblastoma and p53 gene action, their role in the regulation of cell proliferation and malignant growth inhibition.
Insights
This review covers the discovery and mapping of tumor suppressor genes, also known as antioncogenes. It details the function of retinoblastoma and p53 genes in controlling cell growth and preventing cancer.
Area of Science:
- Oncology
- Molecular Biology
- Genetics