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[Progressive lupus dementia. 2 cases with or without antiphospholipid antibodies]
C Robin1, P M Gonnaud, I Durieu
1Service de Neurologie, Hôpital Neurologique Pierre Wertheimer, Lyon.
Revue Neurologique
|December 1, 1995
Summary
Lupus dementia presents diagnostic challenges, with intellectual decline and white matter changes on MRI. Corticosteroid treatment showed promise for improving symptoms and brain imaging in one case.
Area of Science:
- Neurology
- Immunology
- Radiology
Background:
- Systemic lupus erythematosus (SLE) can affect the central nervous system, leading to neuropsychiatric manifestations like lupus dementia.
- Diagnosing neurolupus can be challenging, with limitations in applying established criteria such as the American Rheumatism Association (ARA) criteria.
- Neuroimaging plays a crucial role in identifying brain involvement in SLE patients.