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Candidate Gene Testing in Clinical Cohort Studies with Multiplexed Genotyping and Mass Spectrometry
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Published on: June 21, 2018

Multivariate genetic analysis of an oligogenic disease

S O Moldin1, P Van Eerdewegh

  • 1Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri 63110, USA.

Genetic Epidemiology
|January 1, 1995
PubMed
Summary

Joint segregation and linkage analysis successfully mapped disease susceptibility loci for complex traits. This powerful method identified specific genetic regions influencing multiple phenotypes, outperforming analyses of affection status alone.

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