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Lymphocytes--their possible endocrine role in the regulation of fertility
S K Shahani1, S M Gupta, P K Meherji
1Institute for Research in Reproduction (ICMR), Bombay, India.
Abstract
Problem:
Peptide secretion by peripheral lymphocytes obtained from fertile and infertile women.
Method:
LH, FSH, and prolactin were estimated in the serum and culture supernatants obtained from Con-A stimulated human lymphocytes by RIA.
Results:
The levels of LH, FSH and prolactin were low in the culture supernatants obtained from lymphocytes of infertile women, when compared with proven fertile women.
Conclusion:
The results indicated impairment in endocrine functions of lymphocytes obtained from infertile women. This impairment in lymphocyte function could be one of the causes of infertility in these women.