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Updated: Aug 14, 2026

Evaluation of Planar-Cell-Polarity Phenotypes in Ciliopathy Mouse Mutant Cochlea
Published on: February 21, 2016
Spatial selectivity in a rotationally symmetric model of the electrically stimulated cochlea
J H Frijns1, S L de Snoo, J H ten Kate
1E.N.T. Department, University Hospital Leiden, The Netherlands. J.H.M.Frijns@ent.MedFac.LeidenUniv.nl
Abstract:
A rotationally symmetric model of electrical stimulation of the guinea pig cochlea with active neural elements is used to study the influence of temporal stimulus parameters and electrode configurations on the spatial selectivity of electrical stimulation by cochlear implants. The width of the excitation patterns is determined with respect to the position of the stimulating electrode pairs in the cochlea. Computed O10 AB values are compared against single fibre data from the cat cochlear nerve as measured by Van den Honert and Stypulkowsky (1987). It turns out that the use of charge-balanced asymmetric rather than symmetric biphasic pulses approximately doubles the number of independent channels that can be applied in a cochlear implant with longitudinal bipolar electrodes, like a configuration with radial electrode pairs using symmetric biphasic pulse stimulation will also do. Finally, the influence on Selectivity of the physiological variation in diameter of the cochlear nerve fibres and of a possible loss of their peripheral processes is studied.
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