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Updated: Oct 21, 2026

High-resolution Structural Magnetic Resonance Imaging of the Human Subcortex In Vivo and Postmortem
Published on: December 30, 2015
Estimation of in vivo proton intrinsic and cross-relaxation rate in human brain
1Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan, Republic of China.
Abstract:
By using on-resonance binomial pulse saturation of the immobile component in tissues and by monitoring the time development of the longitudinal decay of the free water magnetization, it has been shown that it is possible to estimate physical model parameters not directly measurable by conventional methods. Since pulsed saturation is easy and safe to implement in a clinical MRI machine, it should be possible to estimate these parameters in vivo by the same means. In this article, we report the results of such estimates of the parameters of the principal components (gray and white matter) in brains of two normal volunteers.
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