Advanced prostate cancer. Endocrine therapies and palliative measures

Area of Science:

• Oncology
• Urology

Background:

• Metastatic prostate cancer management requires a distinct approach compared to other solid tumors.
• The urologist typically manages prostate cancer, leaving primary care physicians (PCPs) with supportive roles.

Purpose of the Study:

• To outline the role of PCPs in managing patients with metastatic prostate cancer.
• To emphasize the importance of PCP familiarity with various treatment modalities.

Main Methods:

• Review of current management strategies for metastatic prostate cancer.
• Discussion of common hormone therapies and their side effects.

Main Results:

• PCPs primarily manage pain and side effects associated with hormone therapies.
• Knowledge of treatments like orchiectomy, estrogens, luteinizing hormone-releasing hormone agonists, and antiandrogens is crucial for PCPs.

Conclusions:

• PCPs can significantly contribute to individualized treatment decisions for metastatic prostate cancer patients.
• Understanding treatment options empowers PCPs to support patients based on their specific condition, comorbidities, age, and values.