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Related Experiment Videos

Local ischemia causes carcinoma-like changes of the rectum

T Jeck1, H Sulser, M Heer

  • 1Department of Internal Medicine, Kantonsspital, Winterthur, Switzerland.

Diseases of the Colon and Rectum
|September 1, 1996
PubMed
Summary

Rectal ischemia can mimic cancer, presenting as "ischemic pseudocarcinoma." This condition, though rare, requires careful diagnosis as symptoms may resolve or require intervention for severe complications.

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Area of Science:

  • Gastroenterology
  • Colorectal Surgery
  • Pathology

Background:

  • Bioptic specimens of rectal cancer typically show malignancy.
  • Endoscopic findings can suggest colorectal cancer, but histological confirmation is crucial.

Purpose of the Study:

  • To describe the clinical features, histological findings, and long-term outcomes of patients with suspected rectal cancer.
  • To investigate cases where endoscopic findings indicated malignancy, but histology did not confirm cancer.

Main Methods:

  • Retrospective review of eight patients with a clinical diagnosis of colorectal cancer.
  • Analysis of clinical presentation, endoscopic findings, histological results, and patient follow-up data.

Main Results:

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  • All eight patients presented with macroscopic findings suggestive of colorectal cancer.
  • Histological examination revealed signs of intestinal ischemia, not malignancy, in all cases.
  • Five patients experienced complete symptom resolution; three had persistent discomfort, and one required proctectomy due to stenosis.

    • Conclusions:

    • Ischemic pseudocarcinoma is a rare but important differential diagnosis for rectal cancer.
    • The prognosis for ischemic pseudocarcinoma is generally favorable.
    • Surgical intervention may be necessary for patients with chronic symptoms or complications like stenosis.