Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Rapid HbA1c testing in a community setting

J S Carter1, C A Houston, S S Gilliland

  • 1Department of Medicine, University of New Mexico School of Medicine, Albuquerque 87131, USA.

Diabetes Care
|July 1, 1996
PubMed
Summary

The DCA 2000 analyzer provides accurate hemoglobin A1c (HbA1c) results for diabetes management in community settings. Nonmedical personnel can reliably operate the device, ensuring valid glycemic control measurements.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A phase I trial of paclitaxel, cisplatin, and veliparib in the treatment of persistent or recurrent carcinoma of the cervix: an NRG Oncology Study (NCT#01281852).

Annals of oncology : official journal of the European Society for Medical Oncology·2016
Same author

Effects of surgical and chemical sterilization on the behavior of free-roaming male dogs in Puerto Natales, Chile.

Preventive veterinary medicine·2015
Same author

Changes in blood testosterone concentrations after surgical and chemical sterilization of male free-roaming dogs in southern Chile.

Theriogenology·2015
Same author

Finding tuberculosis in high schools.

Bulletin - National Tuberculosis Association·2014
Same author

Necrosuppurative orchitis and scrotal necrotizing dermatitis following intratesticular administration of zinc gluconate neutralized with arginine (EsterilSol) in 2 mixed-breed dogs.

Veterinary pathology·2013
Same author

Evidence of placental haemorrhage and preterm delivery.

BJOG : an international journal of obstetrics and gynaecology·2010

Area of Science:

  • Clinical Chemistry
  • Point-of-Care Testing
  • Diabetes Management

Background:

  • Community-based diabetes education programs are crucial for managing glycemic control.
  • Hemoglobin A1c (HbA1c) is a key indicator of long-term average blood glucose levels.
  • Accurate and reliable HbA1c measurements are essential for effective diabetes care.

Purpose of the Study:

  • To evaluate the validity and reliability of the DCA 2000 analyzer for HbA1c testing.
  • To assess the performance of the DCA 2000 when operated by nonmedical personnel in a community setting.
  • To determine if the DCA 2000 is suitable for use in the Native American Diabetes Project.

Main Methods:

  • Trained community members operated the DCA 2000 analyzer on participants in the Native American Diabetes Project.

Related Experiment Videos

  • Two capillary blood samples were collected for duplicate HbA1c measurements.
  • DCA 2000 results were compared against a high-performance liquid chromatography (HPLC) reference system.
  • Validity and reliability metrics, including Pearson correlation coefficients and intraclass correlation coefficients, were calculated.

    • Main Results:

    • High validity was observed, with absolute relative differences between DCA 2000 and HPLC of 4.0% (1994) and 2.0% (1995).
    • Excellent reliability was demonstrated, with intraclass correlation coefficients of 0.959 (1994) and 0.975 (1995).
    • Extending the DCA 2000 analyzer's warm-up period to 60 minutes improved both validity and reliability, particularly for higher HbA1c values.

    Conclusions:

    • The DCA 2000 analyzer provides valid and reliable HbA1c results in community settings when operated by nonmedical personnel.
    • The device is suitable for use in diabetes education programs like the Native American Diabetes Project.
    • Optimizing the analyzer's warm-up protocol enhances measurement accuracy and consistency.