Related Experiment Videos
Control of hepatic bleeding with microfibrillar collagen
Archives of Surgery (Chicago, Ill. : 1960)
|August 1, 1977
Summary
Microfibrillar (Avitene) is an absorbable hemostatic agent effective for diffuse small vessel hepatic bleeding. This agent aids in platelet entrapment and clotting factor activation, proving life-saving in complex cases.
Area of Science:
- Surgical Innovation
- Biomaterials Science
- Hepatology
Background:
- Topical hemostatic agents are crucial for managing surgical bleeding.
- Microfibrillar collagen (Avitene) offers a novel approach to hemostasis.
- Understanding its efficacy in hepatic bleeding is essential.
Purpose of the Study:
- To evaluate the clinical efficacy of microfibrillar (Avitene) as a topical hemostatic agent.
- To assess its performance in diverse hepatic bleeding scenarios.
- To determine its utility in patients with coagulopathies.
Main Methods:
- Clinical use of microfibrillar (Avitene) in 36 patients with hepatic bleeding.
- Application on various bleeding sites including gallbladder fossa, lacerations, and tumors.
- Observation of hemostatic coagulum formation and bleeding control.
Main Results:
- Effective hemostasis achieved in 35 out of 36 patients.
- Successful control of diffuse small vessel bleeding from diverse hepatic etiologies.
- Demonstrated utility in patients with cirrhosis and coagulopathies.
Conclusions:
- Microfibrillar (Avitene) is a safe and effective topical hemostatic agent for diffuse small vessel hepatic bleeding.
- It is particularly valuable in patients with coagulopathies and cirrhosis.
- While not for major hemorrhage, it can be life-saving in specific clinical situations.