Serologic screening for syphilis. Rationale, cost, and realpolitik

G P Schmid1

  • 1Division of STD Prevention, National Center for STD, HIV and TB Prevention, (proposed), Centers for Disease Control and Prevention, Atlanta, GA 30333, USA.

Summary

This paper explores the rationale and cost considerations of syphilis serologic screening. It explains how screening can prevent costly late-stage complications but has limited impact on public health transmission. The decision to screen is largely economic, with an undetermined prevalence threshold. Targeted screening is often used to focus efforts on high-yield populations. The study emphasizes the importance of considering both direct and opportunity costs when allocating resources. Broader syphilis control must also account for other public health priorities.

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