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Antiinflammatory activity of topically applied sertaconazole nitrate
J Agut1, N Tarrida, A Sacristán
1Ferrer International Research Center, Barcelona, Spain.
Abstract:
The antiinflammatory activity of topically applied sertaconazole nitrate was investigated. The dermal administration of 2% sertaconazole to rats, in which edema was induced by application of croton oil in the external ear, induced a 39.8% reduction of edema. The results show that sertaconazole applied by topical route at the concentration at which it is used in clinic, has antiinflammatory action in this experimental model.