Related Experiment Videos
Poliovirus: new insights from an old paradigm
1Committee for Higher Degrees in Biophysics, Harvard University, Cambridge, MA 02138, USA.
Structure (London, England : 1993)
|July 15, 1996
Abstract:
A combination of structural and genetic studies of poliovirus suggests that the final stages of viral assembly lock the virus in a metastable structure primed to undergo the receptor-catalyzed conformational changes required for cell entry. Future studies promise to provide detailed insights into the conformational dynamics of the virion during its life cycle.