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Updated: Jul 31, 2026

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Method for Simultaneous fMRI/EEG Data Collection during a Focused Attention Suggestion for Differential Thermal Sensation
Published on: January 5, 2014
Topographic EEG mapping of the relaxation response
G D Jacobs1, H Benson, R Friedman
1Mind/Body Medical Institute, Deaconess Hospital/Harvard Medical School, Boston, Massachusetts 02215, USA.
Summary
The relaxation response (RR) significantly reduced frontal brain activity in novice subjects. This finding suggests the RR can decrease cortical activation in anterior brain regions.
Area of Science:
- Neuroscience
- Psychophysiology
Background:
- The relaxation response (RR) is a psychophysiological state with potential central nervous system benefits.
- Understanding the neural correlates of the RR is crucial for its therapeutic application.
Purpose of the Study:
- To investigate the central nervous system effects of the RR in individuals new to the practice.
- To quantify changes in electroencephalographic (EEG) activity during RR elicitation.
Main Methods:
- A within-subjects design was employed with 20 novice participants.
- Participants listened to RR and control audiotapes in a counterbalanced order.
- Topographic EEG mapping was used to record brain activity from 14 scalp locations.
Main Results:
- The RR condition led to a statistically significant reduction (p < .0164) in frontal EEG beta activity compared to the control.
- No significant differences in other frequency bands or scalp regions were observed.
Conclusions:
- Eliciting the RR can induce significant reductions in cortical activation, specifically in the anterior brain regions.
- These findings highlight the neural impact of the RR in novice practitioners.

