Related Experiment Videos
Propafenone pharmacokinetics and pharmacodynamics in patients with sustained ventricular tachycardia
A M Gillis1, D G Wyse, L B Mitchell
1Division of Cardiology, Foothills Hospital, Calgary, Alberta, Canada.
The American Journal of Cardiology
|September 1, 1996
Abstract:
The myocardium accumulation and pharmacodynamics of propafenone were evaluated during intravenous infusion in 6 patients undergoing electrophysiologic study for evaluation of ventricular tachycardia. The myocardial accumulation of propafenone was delayed and resulted in nonlinear arterial concentration-effect relations.