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Patient controlled oral analgesia with morphine
H W Striebel1, M Römer, A Kopf
1Department of Anaesthesiology and Intensive Care Medicine, Benjamin Franklin Medical Center, Free University of Berlin, Germany. anae@ukbf.fu-berlin.de
Summary
Patient controlled oral analgesia (PCORA) effectively manages postoperative pain. The PCORA device allows patients to self-administer oral morphine, leading to decreased pain intensity compared to standard care.
Area of Science:
- Anesthesiology
- Pharmacology
- Pain Management
Background:
- Effective postoperative pain management is crucial for patient recovery.
- Demand titration for oral opioids allows for personalized pain relief.
- Current methods may not always provide optimal patient-controlled analgesia.
Purpose of the Study:
- To introduce a novel device for patient-controlled oral analgesia (PCORA).
- To evaluate the efficacy of PCORA for oral titration of morphine in postoperative pain.
- To compare PCORA with customary prescribed pain therapy (CPPT).
Main Methods:
- A modified Baxter-PCA-on-demand system was adapted for PCORA.
- A randomized, cross-over trial involving 20 orthopedic patients was conducted.
- Pain intensity and side effects were assessed at 30-minute intervals.
Main Results:
- The PCORA device demonstrated a bolus volume accuracy of 89.2%.
- PCORA significantly decreased pain intensity over time, unlike CPPT.
- Morphine consumption was comparable between PCORA and CPPT groups.
Conclusions:
- Patient-controlled oral analgesia is an effective and non-invasive postoperative pain management strategy.
- The developed PCORA device is reliable and user-friendly.
- PCORA offers a promising approach to optimizing postoperative pain control.