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Myosin and kinesin: mother and child reunited
1Department of Biological Sciences, Carnegie Mellon University, Pittsburgh, PA 15214, USA.
Chemistry & Biology
|July 1, 1996
Abstract:
The recent solution of the crystal structure of the kinesin motor domain reveals striking similarities to the core region of the myosin motor domain, implying a strong evolutionary relationship between these two motors. However, a complete understanding of the way that motility is generated will require additional structural information, which may explain how the two motors have adapted to their fundamentally different linear substrates, F-actin and microtubules.