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Chemokine receptors - the new frontier for AIDS research
T N Wells1, A E Proudfoot, C A Power
1Geneva Biomedical Research Institute, Glaxo Wellcome Research and Development, 14 Chemin des Aulx, 1228 Plan les Ouates, Geneva, Switzerland.
Chemistry & Biology
|August 1, 1996
Abstract:
CD4 is widely known as the HIV receptor, but is insufficient to allow viral infection. Recently, members of the family of chemokine receptors have been identified as the missing co-receptors, which act with CD4 to allow the virus to enter cells. These discoveries open up the possibilities of novel therapeutic strategies to combat HIV infection and AIDS.