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Anaerobic exercise components during the force-velocity test in sickle cell trait
A Bilé1, D Le Gallais, B Mercier
1Laboratoire de Physiologie des Interactions, Hôpital Arnaud de Villeneuve, Montpellier, France.
International Journal of Sports Medicine
|May 1, 1996
Summary
Subjects with sickle cell trait (SCT) show no differences in anaerobic exercise performance or metabolism compared to those with normal hemoglobin. This study did not support the hypothesis of higher anaerobic metabolism in SCT individuals during strenuous exercise.
Area of Science:
- Exercise Physiology
- Sports Medicine
- Hematology
Background:
- Previous research indicated similar exercise capacity (EC) and maximal oxygen uptake (VO2max) in sickle cell trait (SCT) and normal hemoglobin (Hb) individuals during incremental tests.
- However, during strenuous exercise, SCT individuals exhibit lower oxygen uptake (VO2), suggesting potential metabolic adaptations like increased anaerobic metabolism.
Purpose of the Study:
- To investigate differences in anaerobic exercise performance and metabolism between sedentary males with SCT and matched controls with normal Hb.
- To determine if SCT individuals develop a higher anaerobic metabolism to compensate for reduced oxygen availability during intense exercise.
Main Methods:
- A force-velocity (FV) test on a cycle ergometer was used to assess anaerobic performance and metabolism.
- Participants included 9 sedentary males with SCT and 9 matched controls with normal Hb, matched for morphological, hematological, and aerobic fitness variables.
- Parameters measured included peak anaerobic power (PAnP), maximal velocity (V0), maximal braking force (F0), blood lactate concentrations, and blood lactate kinetics.
Main Results:
- No significant differences were found between SCT and control groups in PAnP, V0, or F0.
- Blood lactate concentrations at PAnP and peak lactate, as well as blood lactate kinetics during the FV test and recovery, were similar between groups.
- These findings indicate comparable anaerobic exercise performance and metabolism in sedentary SCT and normal Hb individuals.
Conclusions:
- Sedentary individuals with sickle cell trait do not exhibit enhanced anaerobic exercise performance or metabolism compared to controls with normal hemoglobin.
- The hypothetical higher anaerobic metabolism in SCT individuals during strenuous exercise was not confirmed by this study.
- Further research may be needed to explore metabolic responses in active SCT populations or during different exercise intensities.