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Antiretroviral drug resistance: mechanisms, pathogenesis, clinical significance
1San Diego Veterans Affairs Medical Center, La Jolla, California, USA.
Advances in Experimental Medicine and Biology
|January 1, 1996
Abstract:
The contribution of HIV drug resistance to treatment failure, the relationship of drug resistance to pathogenesis and the impact of resistance in the role of the promising new class of protease inhibitors remain areas of active investigation. A more precise understanding of these aspects of antiretroviral drug resistance will permit the more effective use of available drugs and the design of new drugs and drug regimens.