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Telomere shortening, ageing, and chromosome damage
M H Kormann-Bortolotto1, B Borsatto, M Smith
1UNIFESP-Escola Paulista de Medicina, Depto. de Morfologia, São Paulo, SP, Brazil.
Mechanisms of Ageing and Development
|July 31, 1996
Abstract:
A relationship between telomere shortening and ageing has been established. A series of young and elderly healthy donors. Alzheimer disease patients, young and old Down's syndrome individuals were cytogenetically analyzed. No preferential damage in distal bands was seen in age-related chromosome instability.