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Hodgkin's disease: a clinicopathologic study

R Rana1, R Chopra, K Masih

  • 1Christian Medical College, Ludhiana.

Indian Journal of Pathology & Microbiology
|July 1, 1995
PubMed
Summary
This summary is machine-generated.

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This study analyzed 104 Hodgkin's disease cases, finding a male predominance and most patients under 50. Mixed cellularity was the most frequent subtype, while lymphocyte depletion was least common.

Area of Science:

  • Oncology
  • Epidemiology
  • Pathology

Background:

  • Hodgkin's disease is a cancer of the lymphatic system.
  • Understanding the epidemiological and pathological characteristics of Hodgkin's disease is crucial for effective treatment strategies.

Purpose of the Study:

  • To analyze the clinical and pathological features of Hodgkin's disease in a specific patient cohort.
  • To compare regional and global trends in Hodgkin's disease subtypes and demographics.

Main Methods:

  • Retrospective analysis of 104 Hodgkin's disease cases diagnosed between July 1981 and June 1991.
  • Categorization of cases based on histological subtypes and patient demographics (age, sex).

Main Results:

  • A male preponderance was observed in the studied population.

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  • The majority of patients (82.7%) were under 50 years of age.
  • Mixed cellularity (57.7%) was the most common histological type, followed by nodular sclerosis and lymphocyte predominant (16.3% each). Lymphocyte depletion was the least common (9.7%).

    • Conclusions:

    • The findings highlight specific demographic and histological patterns of Hodgkin's disease in the region.
    • Comparison with global data provides insights into potential variations in disease presentation and prevalence.