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Adaptation of a conjugal transfer system for the export of pathogenic macromolecules
S C Winans1, D L Burns, P J Christie
1Section of Microbiology, Cornell University, Ithaca, NY 14853, USA. scw2@cornell.edu
Trends in Microbiology
|February 1, 1996
Abstract:
Conjugal transfer of bacterial plasmids requires a pore through which DNA can traverse the envelopes of the donor and recipient cells. Recent studies indicate that these pores, which are composed of approximately ten proteins, are evolutionarily related to the transport systems required for the transfer of oncogenic T-DNA from Agrobacterium tumefaciens to plant cells and for toxin secretion from Bordetella pertussis.