Abdominal pain in infants and children
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Updated: Nov 4, 2026

Electrophysiological Measurements and Analysis of Nociception in Human Infants
Published on: December 20, 2011
1Division of Pediatric Surgery, Mayo Clinic Rochester, Minnesota 55905, USA.
Insights
Most childhood abdominal pain resolves on its own, often from benign causes. Identifying rare, serious conditions requires careful evaluation, especially in infants with bilious vomiting. Further studies are seldom needed.
Area of Science:
- Pediatrics
- Gastroenterology
Background:
- Childhood abdominal pain presents a diagnostic challenge, balancing common benign conditions with rare, severe ones.
- Effective management requires differentiating self-limiting illnesses from life-threatening causes.
Purpose of the Study:
- To outline a diagnostic approach for childhood abdominal pain.
- To emphasize the importance of age-specific evaluation and clinical assessment.
Main Methods:
- Categorization of diagnostic strategies based on age groups: infants, preschoolers, and school-age children.
- Clinical appraisal of symptoms and thorough physical examination are primary tools.
- Limited use of laboratory or radiologic studies.
Main Results:
- Bilious vomiting in infants indicates potential surgical emergencies.
- Gastroenteritis, constipation, and reflux are common nonsurgical causes.
- Serious conditions like appendicitis affect a small fraction (approx. 1 in 15) of school-aged children.
Conclusions:
- Most childhood abdominal pain cases are self-limiting and benign.
- A detailed history and physical exam are crucial for accurate diagnosis.
- Diagnostic studies are infrequently required, underscoring the importance of clinical judgment.
Abstract:
The challenges of childhood abdominal pain are to treat the majority of children with self-limited conditions of obscure but benign causes and to identify the child with a rare, life-threatening cause of pain. The diagnostic algorithm of abdominal pain during childhood is best compartmentalized into three groups: infants, preschoolers, and school-age children. In infants, bilious vomiting heralds a life-threatening or surgically indicated disorder. Most nonsurgical conditions are related to gastroenteritis, constipation, and reflux. The majority of children with abdominal pain experience spontaneous resolution of their symptoms without specific management. For every 15 school-age children with abdominal pain, 1, at most, will have a serious condition such as appendicitis. Parents and children appreciate a careful appraisal of the symptoms, and the physician should listen to their concerns and perform a thorough examination. Laboratory or radiologic studies are rarely indicated.
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