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Related Experiment Videos

Nail infections

G Midgley1, M K Moore

  • 1Department of Medical Mycology, St. Thomas' Hospital, London, United Kingdom.

Dermatologic Clinics
|January 1, 1996
PubMed
Summary
This summary is machine-generated.

Accurate laboratory identification of fungal pathogens is crucial for treating onychomycoses, especially with emerging nondermatophyte molds. Proper diagnosis ensures effective selection of antifungal agents for optimal patient outcomes.

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Area of Science:

  • Mycology
  • Medical Mycology
  • Infectious Diseases

Background:

  • Onychomycoses (fungal nail infections) are increasingly prevalent.
  • A wider range of fungal organisms are now recognized as pathogens.
  • Nondermatophyte molds like Scytalidium dimidiatum are common in certain regions.

Purpose of the Study:

  • To emphasize the necessity of accurate laboratory identification of fungal pathogens causing onychomycoses.
  • To highlight the role of nondermatophyte molds in onychomycosis.
  • To underscore the importance of precise pathogen identification for effective antifungal treatment selection.

Main Methods:

  • Review of current literature on onychomycosis etiology and diagnosis.
  • Analysis of reported cases involving various fungal species, including dermatophytes and nondermatophyte molds.

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  • Discussion of the clinical implications of accurate fungal identification.
  • Main Results:

    • Dermatophyte and Candida species remain common causes of onychomycosis.
    • Nondermatophyte molds (e.g., Scytalidium dimidiatum, Scopulariopsis, Acremonium, Aspergillus) are significant pathogens, particularly in specific geographic areas.
    • Accurate identification is essential due to the availability of diverse antifungal agents.

    Conclusions:

    • Accurate laboratory identification of the causative fungus is essential for effective onychomycosis treatment.
    • The spectrum of fungal pathogens responsible for onychomycosis is expanding.
    • Precise diagnosis guides the selection of appropriate antifungal therapy, improving treatment efficacy.