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Changes in the surface carbohydrate composition and exposure of anionic groups caused by beta-lactam antibiotics in
A M Figueiredo1, B T Ferreira-Carvalho, C S Alviano
1Instituto de Microbiologia, Universidade Federal do Rio de Janeiro, Brazil.
The Journal of Antimicrobial Chemotherapy
|December 1, 1995
Abstract:
Upon the addition of beta-lactam antibiotics at concentrations that caused a 50% reduction in the dry weight, beta-haemolytic streptococci produced increased amount of rhamnose, though the hexosamine content remained unchanged. These sugars are components of C-carbohydrate. Sialic acid content also increased in group B streptococcal surfaces and penicillin treatment generated new accessible surface sialic acid residues.