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Inherited predisposition to colorectal neoplasia
B M Stephenson1, N R Hall, P J Finan
1Cardiff Royal Infirmary.
British Journal of Hospital Medicine
|January 1, 1994
Abstract:
This review concentrates on the genetics of colorectal neoplasia. There is now a greater understanding of the molecular genetics of the inherited condition familial adenomatous polyposis and of the adenoma-carcinoma sequence in non-inherited colorectal cancer. We consider the evidence that sporadic colorectal cancer may also have an underlying genetic susceptibility.