Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Zinc and growth

Y Nishi1

  • 1Department of Pediatrics, Hiroshima Red Cross Hospital, Japan.

Journal of the American College of Nutrition
|August 1, 1996
PubMed
Summary
This summary is machine-generated.

Zinc deficiency impairs growth and sexual function by affecting growth hormone (GH) and insulin-like growth factor-I (IGF-I) metabolism. Understanding these complex interactions is crucial for addressing related health issues.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Endotoxin activity and leukocytic STAT3 mRNA alterations differ according to age in lipopolysaccharide-challenged calves.

Research in veterinary science·2022
Same author

Subjective Evaluation of Denture Adhesives: A Multicenter Randomized Controlled Trial.

JDR clinical and translational research·2019
Same author

Molecular and clinical characterization of glucokinase maturity-onset diabetes of the young (GCK-MODY) in Japanese patients.

Diabetic medicine : a journal of the British Diabetic Association·2014
Same author

Multi-level control of conductive nano-filament evolution in HfO2 ReRAM by pulse-train operations.

Nanoscale·2014
Same author

Structure of the genomic DNA encoding cucumber ascorbate oxidase and its expression in transgenic plants.

Plant cell reports·2013
Same author

Posterior capsule opacification following 20- and 23-gauge phacovitrectomy (posterior capsule opacification following phacovitrectomy).

Eye (London, England)·2012
Same journal

Response to Commentary.

Journal of the American College of Nutrition·2021
Same journal

Risk of Osteoarthritis is Positively Associated with Vitamin D Status, but Not Bone Mineral Density, in Older Adults in the United States.

Journal of the American College of Nutrition·2021
Same journal

Nutrient Intake and Muscle Measures in Geriatric Outpatients.

Journal of the American College of Nutrition·2021
Same journal

Analyzing Blood Pressure Ascent during Aging in Non-Diabetics: Focusing on Links to Insulin Resistance and Body Fat Mass.

Journal of the American College of Nutrition·2021
Same journal

Effect of a Free-Living Ketogenic Diet on Feasibility, Satiety, Body Composition, and Metabolic Health in Women: The Grading Level of Optimal Carbohydrate for Women (GLOW) Study.

Journal of the American College of Nutrition·2021
Same journal

The Prophylactic Activity of <i>Punica granatum</i> L. mesocarp Protects Preadipocytes against Ribosylated BSA-Induced Toxicity.

Journal of the American College of Nutrition·2021
See all related articles

Area of Science:

  • Endocrinology
  • Nutritional Science
  • Human Physiology

Background:

  • Zinc is vital for normal growth and sexual development.
  • Zinc deficiency is linked to growth retardation and hypogonadism.
  • Complex interactions exist between zinc, growth, and hormonal regulation.

Purpose of the Study:

  • To explore the mechanisms linking zinc deficiency to impaired growth and sexual function.
  • To investigate the role of the growth hormone (GH)-insulin-like growth factor-I (IGF-I) axis in zinc deficiency.
  • To elucidate the intricate relationship between zinc, GH, and gonadal function.

Main Methods:

  • Literature review on zinc metabolism and its effects on endocrine systems.
  • Analysis of studies investigating zinc's impact on GH production and IGF-I levels.

Related Experiment Videos

  • Examination of research on zinc's role in bone and gonadal development.

    • Main Results:

    • Zinc deficiency can reduce GH production and/or IGF-I levels.
    • Impaired bone metabolism and gonadal function are associated with zinc deficiency.
    • The interplay between zinc, GH-IGF-I axis, and reproductive health is multifaceted.

    Conclusions:

    • Zinc is essential for maintaining normal growth and sexual function.
    • Zinc deficiency disrupts the GH-IGF-I axis and negatively impacts gonadal function.
    • Further research is needed to fully understand the complex interrelationships involved.