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Updated: Aug 12, 2026

Tractable Mammalian Cell Infections with Protozoan-primed Bacteria
Published on: April 2, 2013
The molecular ecology of legionellae
1Division of Bacterial and Mycotic Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA. bsf2@ciddbd2.em.cdc.gov
Abstract:
Legionella pneumophila is the most highly characterized member of a genus of bacteria that survive as intracellular parasites of freshwater protozoa. These bacteria can also multiply intracellularly in human phagocytic cells and cause respiratory disease in humans. Comparison of the invasive strategies of L. pneumophila in mammalian and protozoan cells and study of the interactions between Legionella and protozoa should prove useful in development of strategies for the prevention of legionellosis.
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