[The effect of antibodies to S-100 proteins on synaptogenesis processes and learning in rats]

In newborn rats passively immunised with the brain-specific protein (BSP) S-100, obvious ultrastructural changes occurred in the glial cells, density of desmosomal contacts increased and the density of synaptic contacts in neurophile of the supraoptic nuclei of the hypothalamus decreased. The S-100 proteins seem to fulfil a regulatory function in synaptogenesis in both newborn and adult animals.