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[Angioid streaks. Pathogenesis and the clinical picture]
H Janotka1, J Hess, J Włodarczyk
1Z Oddziału Okulistycznego Szpitala im. Stefana Zeromskiego w Krakowie.
Klinika Oczna
|September 1, 1995
Summary
Angioid streaks are irregular breaks in Bruch's membrane, not present at birth. They can progress to vision-threatening conditions like macular degeneration.
Area of Science:
- Ophthalmology
- Genetics
- Pathology
Context:
- Angioid streaks are pathological changes in the fundus.
- Histopathology and diagnostic techniques have evolved since their initial description in 1889.
Purpose:
- To provide a comprehensive overview of angioid streaks.
- To discuss their clinical presentation, progression, and associated conditions.
Summary:
- Angioid streaks are not congenital, with the earliest sign being "peau d'orange".
- Progression can lead to disciform macular degeneration, peripapillary atrophy, or choroidal sclerosis.
- Trauma can precipitate macular hemorrhage and angioid streaks.
Impact:
- Highlights the association of angioid streaks with systemic diseases like pseudoxanthoma elasticum, Paget's disease, and hemoglobinopathies.
- Emphasizes the importance of recognizing angioid streaks for diagnosing underlying conditions.